Dermal neurofibromas (sometimes referred to as cutaneous neurofibromas) originate in nerves in the skin. Three kinds are distinguished:
- Discrete cutaneous neurofibromas: Sessile or pedunculated masses on the skin, which are fleshy and non-tender, and can vary in size.
- Discrete subcutaneous neurofibromas: Lie below and look like bumps on the skin, which can sometimes be tender.
- Deep nodular neurofibromas: Involving tissues and organs underneath the dermis, but otherwise resembling cutaneous and subcutaneous neurofibromas.
Age of onset
Dermal neurofibroma typically arise in the teenage years and are often associated with the onset of puberty. They continue to increase in number and size throughout adulthood, although there are limits to how big they get.
Dermal neurofibromas can lead to stinging, itching, pain and disfiguration.